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SRP423465: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10459514/

MRSA collected from patients and healthcare workers (HCWs) from public hospitals in Benin between 2019 and 2021.

SRP328068: https://www.journalofhospitalinfection.com/article/S0195-6701(21)00305-4/fulltext

Methicillin-resistant Staphylococcus aureus transmission among healthcare workers, patients and the environment in a large acute hospital under non-outbreak conditions investigated using whole-genome sequencing

ERP106634: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546718/ 

Methicillin resistant Staphylococcus aureus (MRSA) can cause life-threatening conditions that are difficult to treat, and which can be both hospital and community acquired. MRSA displays a clonal yet dynamic population structure, with clones emerging both in hospitals and the community and replacing existing clones. Whole Genome Sequencing (WGS) has been successfully applied to study local and global spread of MRSA, yet studies employing WGS are rare in developing countries, mainly due to cost and gaps in expertise. This study will conduct the retrospective sequencing of MRSA isolates from Latin America to investigate their population structure and compare to clones circulating globally. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

SRP325909: https://www.nature.com/articles/s41598-022-08230-z 

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) poses an important threat in human and animal health. In this study, we ask whether resistance and virulence genes in S. aureus are homogeneously distributed or constrained by different animal hosts. We carried out whole genome sequencing of 114 S. aureus isolates from ten species of animals sampled from four New England states (USA) in 2017-2019. The majority of the isolates came from cats, cows and dogs. The maximum likelihood phylogenetic tree based on the alignment of 89,143 single nucleotide polymorphisms of 1173 core genes reveal 31 sequence types (STs). The most common STs were ST5, ST8, ST30, ST133 and ST2187. Every genome carried at least eight acquired resistance genes. Genes related to resistance found in all genomes included norA (fluoroquinolone), arlRS (fluoroquinolone), lmrS (multidrug), tet(38) (tetracycline) and mepAR (multidrug and tigecycline resistance). The most common superantigen genes were tsst-1, sea and sec. Acquired antibiotic resistance (n =10) and superantigen (n = 9) genes of S. aureus were widely shared between S. aureus lineages and between strains from different animal hosts. These analyses provide insights for considering bacterial gene sharing when developing strategies to combat the emergence of high-risk clones in animal


Relación entre SRA y ID del ensamblado:

Buscar IDs en esta página: https://www.ncbi.nlm.nih.gov/sra

ERR3290986 a1
ERR3290998 a2
ERR3290999 a3
ERR3291000 a4
ERR3291005 a5
SRR14933408 a6
SRR14933421 a7
SRR14933429 a8
SRR14933433 a9
SRR14933451 a10
SRR14933453 a11
SRR14933457 a12
SRR14933458 a13
SRR14933459 a14
SRR14933460 a15
SRR14933474 a16
SRR14933479 a17
SRR14933496 a18
SRR14933511 a19
SRR15112692 a20
SRR15422242 a21
SRR15422279 a22
SRR15422301 a23
SRR15422316 a24
SRR15422339 a25
SRR23547056 a26
SRR23547057 a27
SRR23547065 a28
SRR23547098 a29
SRR23547101 a30
SRR23547104 a31


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‘Sequencing types’